Saturday, August 31, 2019

Analysis Of Different Types Of Competition Economics Essay

To travel markets back towards perfect competition, have to hold a really big figure of houses, complete freedom of entry, a homogenous merchandise and perfect cognition of the goods. In the short tally, the supranormal net incomes can be because there is no clip for new houses to prosecute the market. However, the supranormal net incomes will be competed by new houses in the long tally. In the short tally, the demand curve and the supply curve is equal to fringy cost. In the long tally, monetary value is equal to hanker run mean cost. The perfect competition market is a monetary value taker, so the monetary value is non alteration.MonopolyIn monopoly, has merely one house in an industry, restricted or wholly out of use freedom of entry, merely one alone merchandise. Barriers to the entry of new houses is apparent to protect a monopoly from rivals such as economic systems of graduated table, control over supplies of inputs or end products, patents or right of first publication, and t actics to extinguish challengers. Monopoly will acquire maximized monetary values. If the demand curve and cost curve of monopoly are the same of absolutely competitory industry, monopoly will bring forth less and halt at the higher monetary value than absolutely competitory industry to maintain their clients. Potential of rivals is of import such as a house ‘s monetary value and scheme.Monopolistic CompetitionIn monopolistic competition, has a rather big figure of houses, unrestricted freedom of entry, has different sort of merchandises. In the short tally, the houses can gain supranormal net incomes because clients still want to purchase the merchandises even though the monetary value goes up. However, in the long tally, the demand curve will touch the long-term norm cost curve ; it means the monetary value goes up so clients do non desire to purchase the merchandises because their wages still the same degree. Therefore, the houses will non acquire more net incomes. Many hou ses under monopolistic competition can prosecute in non-price competition such as merchandise development and advertisement to keep an advantage over their challengers. Monopolistically competitory houses may hold higher costs than absolutely competitory houses, but clients can acquire different sort of merchandises. Monopolistically competitory houses possibly have fewer economic systems than monopolies and have less research and development, but they can maintain monetary values lower than under monopoly.OligopolyIn oligopoly, has few figure of houses, restricted freedom of entry, has apathetic merchandises or merchandise distinction. Besides the houses under monopolistic competition, there are assorted barriers to the entry but similar to under monopoly.Chapter fourMarket StructuresTable Of ContentssIntroduction†¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ . p. 1Theory†¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ . pp. 2 – 3Part I – Perfect Competition†¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ . pp. 4 – 7Part II – Monopoly†¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ . pp. 8 – 10Part III – Monopolistic Competition†¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ . pp. 11 – 13Part IV – Oligopoly†¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ . pp. 14 – 15Decision†¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ . p. 16Mentions†¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ †¦ . p. 17IntroductionPresents, the market construction of the concern are plentiful and assorted. Classifying markets require each company or house have to understand item clearly to be after the right manner to make concern. As a consequence, market construction has four sorts: Perfect competition, monopoly, monopolistic competition and oligopoly. It can be said, in any states which besides happen to positive and negative of each type. Therefore, chapter Four of Necessities of Economics is traveling to explicate four types of market construction. Besides, the competitions are between companies together is based on what sort of concern and the strength they have from each specific instance. This chapter besides give information about advantage and disadvantage of market construction because some sorts can acquire much net income merely and some sorts have to vie. In peculiar, each house will hold assorted schemes because they will hold assorted challengers and competitions.TheoryThe manner purchasers and providers interacts each other in the industry to make up one's mind the monetary value and the measure is defined as market construction. There are 4 market constructions that have been used in the economic universe: Perfect competition, Monopoly, Monopolistic competition ( Imperfect competition ) and Oligopoly. Perfect competition is the free-entry market in which there are limitless purchasers and Sellerss called monetary value taker. They have no power to command the monetary value of the merchandises which merely based on demand and supply in the market. There is a market that has merely individual marketer. It is stated as Monopoly market where the monetary value is set by one marketer. Example: EVN, Petrolimex†¦ Monopolistic competition or Imperfect competition is similar to hone competition, which has a batch of Sellerss bring forthing a differentiated merchandise. Each can put its ain monetary value and measure ; nevertheless, they are excessively little to act upon the whole market monetary value and measure. Oligopoly is the market which has a little figure of Sellerss in the industry. At least one determination about the monetary value or the measure of one house can count to the others. Finally, when different purchasers buy the merchandise by different monetary value, that statement is defined as monetary value favoritism. In international trading, sometime it can do a dumping[ 1 ].CASE STUDYChapter 4Market STRUTURESPart IPERFECT COMPETITIONThe economic system, in general, is all about competition. Competition is good because it makes clients to be a male monarch who can make up one's mind what productions they will utilize and how quality is that. However, true aims of houses are n't to do the clients to be a male monarch. What they try to make is maximise their net incomes. But in ‘perfect competition market ‘ , the fact is, houses can do supranormal net incomes in the short-term but in the long tally they wo n't do any net incomes. They merely have adequate to remain in concern. Perfect competition is a market construction where all houses produce the same merchandise and noA producerA orA consumerA has the rightA or ability toA controlA theA market, A asA affect the monetary value. Perfect Competition is merely a theory that does n't be in the existent universe because of so many conditions have to be met. However, there are markets that come near to perfect competition market if it has four following conditions. First, there are so many houses or manufacturers that participate in the market and none of them have a right to alter the market monetary value. For case, the market for rice in Vietnam is so broad. Regardless of one husbandman has produced 100 more kgs of rice, the rice market monetary value is still maintained the same. This status of each house being so little that they are undistinguished comparative to the market is what makes the MR curve horizontal or absolutely elastic.[ 2 ] Fringy Revenue curve[ 3 ] One house can bring forth a noticeable sum of end product but it is nil compared to the market. As a consequence, the extra end product the house produces can be sold at the same monetary value as smaller measures of end product. Second, it has to be the market where all houses are selling an indistinguishable merchandise produced in the same manner. When all houses produce an indistinguishable merchandise, they are called homogenous merchandises.[ 4 ]The premise about homogenous merchandises means that all houses will sell their merchandises at the same monetary value. If all the merchandises from different houses are indistinguishable, clients will choose houses by taking the lowest monetary value. Any house that set their monetary value higher than others will lose all its clients. Third, there is no limitation to come in or go out the market means that new houses can easy acquire into the industry every bit good as the older houses can acquire out. In long-term, this is really of import. New houses when they try to come in the industry, there is no other manner to vie with other houses beside of lower their monetary value to pull clients. The existing houses must follow the new lower monetary value in order non to lose clients and after that, supranormal net incomes are no more. That is the ground why in long tally, houses merely make adequate net incomes to remain in the concern. Finally, 4th conditions, is that all houses are to the full cognizant of monetary values, the manner of lower cost of production and market chances and clients know all about the monetary value, the quality of the merchandise at all times.[ 5 ]The economic expert called it by perfect cognition or perfect information. Although Perfect Competition does n't be in any existent economic systems, it is an ideal economic that make the economic become better and more expeditiously. In other words,

Friday, August 30, 2019

Comparing tajfel’s social identity theory and scapegoating theory in explaining prejudice Essay

The issue of comparing and contrasting Tajfel’s theory of social identity and the scapegoating theory in explaining prejudice is a very controversial issue subject to debate .The theories are like one and the same thing though they are different as show be noted as the debate goes on.The main difference is that scapegoating mainly touches on the rivals of in-group against out-group while social identity theory bases on the individual rivalry against individual and both have got a negative prejudice effect. Barbara (1997) reiterates that prejudice by definition is an attitude usually negative toward a member of some other group solely on prejudice the membership in that group . Feldman explains prejudice in the sense that when two groups want to achieve the same goal but both groups cannot get hostility is due to happen .For example increased competition of various groups in times of economic crisis may be one of the factors leading to prejudice .Tajfel (1971) believes that the scapegoating theory is not adequate in explaining prejudice and he also uses a social identity theory . However Tajfel et al (1971) argue that competition is not sufficient for inter-groups conflict and hostility .Tajfel does not deny the importance of competition between groups as explanation for the origins of prejudice but argues that mere perception of the existence of another group can itself produce discrimination .Tajfel et al goes on to say that before any discrimination occur ,people must be categorized as members of in-groups or out-groups but more significantly the very act of of categorization by itself produces conflict and discrimination leading to negative prejudice . Therefore from the above analysis one can be tempted to say that the origins of prejudice in both social identity theory and scapegoating theory arise from the same nature to a greater extent as noted in the argument in question though they might be some differences but to a lesser extent. Moreover, scapegoating theory in explaining prejudice asserts that people or groups seeks to displace their anger on the weaker people or groups .When the weaker group sees that its being dehumanized or being regarded as inferior scapegoating has entered in the danger zone which will eventually lead to the aggression of the out-group. However Tajfel’s social identity theory suggest that individuals strive for self image and social identity that is influenced by the value categorized by a group an individual belongs .Therefore from the aforementioned analysis one might be tempted to conclude that the spirit of pride within one group and an individual’s ego perpetuated by a group an individual belongs may leads to prejudice as expulsed in the argument above. In addition , basing on the scapegoating theory in explaining prejudice ,pain and frustration only often evoke hostility for example the native Africans were allocated land in reserves which was very infertile and this led to the First Chimurenga war when the natives fought the whites blaming them for drought and other misfortunes that they were facing as a result of their presence .In contrast to the above theory, Myers(2008) elucidates that the social identity theory in explaining prejudice suggest that individuals in a group come to develop a sense of their identity that is anchored within in-group . Therefore .from the information above one might tempted to clear that both of the two theories asserts that as a result of aggression by scapegoating and in-group development development as supported by Tajfel(1971) elaborates the concept of prejudice though they vary to a lesser extent as exhibited in the argument in question. More so, Healey (2006) pontificates that the scapegoating theory targets for the displaced aggression vary, for example failure by the government of Zimbabwe to run the economy that led to hyper-inflationary epoch many Zimbabweans blamed the sanctions for the economic turmoil and the Europeans as the oppressors but were there to blame for economic crisis in actual sense and this poses a question to many people . Moreover, in the early 1980s people vented their anger to the witchcraft tradition and leading to the masquerading of tsikamutandas to uproot witches in societies and people who were presumed to be witches were humiliated or forced to drink a concoction and if the witch belongs to in-group and another one from out-group  favoritism was bound to happen leading to someone being unfairly treated due to favoritism .The South Africans felt the shortage of employment in their country is because of Zimbabweans saying that they are taking all jobs thus leading to xenophobia attacks on Zimbabweans and in that essence it evokes prejudice between the in-group and out-group. On the other side of the coin ,Faney (2004) alludes that the social identity theory furnishes favoritism among in-groups and out-groups. The theory asserts that as groups are formed ,they come to develop a culture of patriotism towards themselves and to discriminate against out-groups .therefore , from the aforesaid assertions one might be tempted to alludes that prejudice arise from favoritism and displaced aggression as exposed in both theories above . Furthermore , Tajfel (1971) suggests that resource allocation is done unequally ,in particular they will favor their own group at the expense of out-group .This suggest that the tendency in-favor of in-group may be especially powerful if the in-group feels to be minority .In addition the scapegoating theory in explaining prejudice propounds that for instance in Zimbabwe ,opposition to immigration since 1990 has gone up and down following the hijacking unemployment rate . Moreover ,the scapegoating theory and social identity theory explain the concept of prejudice in a different dimension as noted above in the argument in question though some very small similarities were noted but since the explanations outwit the similarities one might be tempted to conclude that both theories in explaining prejudice they differ immensely . To add more flesh to the bones , the social identity theory presumes that as people hear the views of a group they are bound to change their own views to suite of the in-group and one school of thought believes that similarities within groups will ultimately lend itself to polarization among groups .Members of the in-group will try to make themselves look unique from out-group as they endeavor this uniqueness to prove a spirit of social identity . For example if l am a soccer fan and we are discussing the play of the play of an opposing team , l might advocate for my team that plays much better than the opposing team .However the scapegoating theory reiterates that the strongest anti-black prejudice has occurred among whites who stay  much closer to blacks on the socio-economic hierarchy . For instance the whites who protested for the industrial conciliation act enactment are the whites who were feeling threatened by the black society and those white who were on top of the socio-economic hierarchy felt no intimidation by blacks .there, as thus discussed above one might possibly say that it is clear from the aforesaid argument that scapegoating and social identity theory can explain prejudice from various angles as expulsed in the argument in question . Moreover , Tajfel (1971) asserts that the personal identity deteriorates and social identity become focal in the sense that people have a feeling of themselves individually and as part of the group they belong and in doing so their group identity comes to the central core of their prejudice and they ceases to pay more attention on the individual characteristics of out-group .Furthermore , scapegoating pontificates that the clash of interest may result in prejudice and anyone who is not satisfied with himself is always ready for a revenge .For example Floyd May-weather might always feel that he can outclass Pacquino despite losing to him and every time is ready for a revenge match so as to claim his status as a champion . Therefore , from the above analysis one might be tempted to conclude scapegoating and social identity theory are somehow different though clearly explaining the concept of prejudice as noted in the aforesaid assertions . In summation ,It does not need a rocket scientist to discover that competition to prestige, social recognition ,water, land ,jobs and some other resources may precipitates aggression which will eventually turn into prejudice in both theories scapegoating and social individual theory .However , it is an abortion of factual evidence to sidestep the differences such as displaced aggression , feelings of in-group and out-groups , favoritism among in-groups and out-groups and just to mention but a few were addressed as differences of social identity and scapegoating theory as exhibited in the argument in question in explaining the concept of prejudice. ` Tatenda Nyoka is a student at Great Zimbabwe Zimbabwe University and can be contacted on tatendanyoka@gmail.com

Print Media Versus Electronic Media Relations Essay

Print media today is still considered to be the number one medium for public relations practitioners, despite the recent progress were seeing in electronic media and especially the Internet. Public relations practitioners channel any pertinent information through the media in order to send it to its target audiences or shareholders in the company. Public relations professionals mostly deal with print media. Print media is considered an important function for public relations professionals because many newspaper and magazine agencies use new releases. Before the terrible attacks on the World Trade Center in New York City on September 11, 2001 newspaper readership had been steadily declining in the United States and the rest of the world. After September 11, 2001 newspapers readership had improved as well the media’s image. Americans suddenly wanted to know to be informed about world affairs, specifically the war on terror and protecting our nation. From â€Å"The Practice of Public Relations† book: 49% considered the media â€Å"highly professional,† compared to 73% after 9/11, 59% considered the media â€Å"politically biased,† compared to 47% after 9/11, and 35% believed the news media â€Å"don’t care† about the people they report on, while 47% found them compassionate. Based on a study done by the U.S. Industry & Market Outlook there are 30,700 printing companies in the United States. As for magazines 17,321 are published in the United States according to the National Directory of Magazines. Furthermore magazine readership has seen an increase in its readership. Now I will begin discussing publicity and its relevance. First, off publicity is known as the conscious attempt to manage the public’s perception of a subject. Publicity is achieved by directly working with media. In addition, publicity is understood a more powerful method than advertising. Advertising cost a lot of money. Think about it a full-page ad in the New York Times or Wall Street Journal could cost a company or an individual thousands of dollars. Publicity cost compared to advertising are very low, it merely  costs a company their time and effort to create. Publicity is considered to be more credible than advertising because it’s similar to a third-party endorsement. Its thought of as â€Å"news† so most people will trust it. There are six reasons why publicity works well for an organization. First one is when announcing a new product or service. Like I said earlier publicity is deemed as news so utilizing publicity before advertising is crucial. Second, publicity can be advantageous when recognizing an old product. Third reason is when explaining a complicated product. This means its tough to explain a multifaceted product in an advertisement because advertisements are limited. Companies cannot possibly fit everything they want into a brief advertisement so they devise a publicity stunt such as a staged event to discuss complex products or services. Fourth value of publicity for any organization is little or no budget. This suggests that companies with small budgets cannot afford to devote there time to advertising, so they turn to publicity, which is rather inexpensive and exceptionally effective. The fifth value of publicity is enhancing the organization’s reputation. This in my opinion is very important job for public relations practitioners. The best way to promote or enhance an organization’s reputation is through publicity and not through advertising because it is self-serving and very ineffective. The last reason why publicity makes good sense for any organization is during a crisis. According to our textbook publicity techniques are the fastest and most credible means of response during a crisis. This is also known as damage control, companies frequently choose this route when a crisis occurs. Now I will discuss another form of public relations that’s taken part of print media, propaganda. First off the purpose of propaganda is to influence people’s opinion and manipulate people to change their behavior, rather than to communicate the facts about something. The early uses of propaganda can be traced all the way back in 1600’s. The Catholic Church used propaganda to inform and persuade the public. Back during those days the term propaganda did not have the same negative connotation like it has today. Propaganda also was used during the days that led to the American Revolution. Thomas Paine, Samuel Adams and many others participated in propagating anti-British  information to the rest of the colonies. Common examples where propaganda can be easily found in newspapers, magazines, pamphlets, government reports, news reports, books, posters, and even art work. Next topic that I will discuss is how to pitch publicity successfully. The public relations textbook outlines 10 rules or tips on how to achieve publicity after writing a release. First tip is to know deadlines. Time means everything especially for newspapers. They need stories sent to them at a precise time so they can follow up on the story to make sure its not phony. Second tip is to write to them directly, do not call. Reporters have a great deal deadlines to make, they don’t need another person calling following up on there release. Therefore, writing them a letter is preferable and considered proper etiquette. The third is to direct the release to a specific person or editor. It would behoove any person sending releases to a newspaper to write which department or specific editor needs to see your release. The reason to direct your release to a specific person is because newspapers consist of many departments and even more reporters and writers. Next one is similar to the last one, which is to determine how the reporter wants to be contacted. This shows the reporter that you care about his or her preferences. Something not to do is to badger an editor to get your story to be published. This is a wrong tactic and it wont further your cause. Badgering could only lead to worse results in the future. The next two are to use exclusives but be careful and make sure you do your own calling. Making your own calls instead of letting an assistant to it is a sign of respect. The next suggestions are to not send clips of other stories about your client and to develop a relationship. Developing a good professional relationship is key to accomplishing things. The better you know a reporter the more successful your company will be. The last rule and in my opinion the most important job for a public relations practitioner is to never lie. Once they lose trust in you the relationship is severed and pretty much over. All in all print media is still regarded as the strongest medium for public relations professionals. Print media can be achieved through publicity and advertising. Organizations should always consider publicity before  advertising because it offers some positive benefits. Furthermore propaganda is the spreading of ideas and information for the purposes of inducing or manipulating behavior. For the most part people believe propaganda is usually false, which isn’t necessary true. The last topic I wrote about was how to pitch publicity effectively to reporters; these rules were outlined in our textbook. Electronic media has become king in the twenty-first century. Fifty percent of the nation gets their news from television. Today there are more then the big three networks. Cable television has become a monster itself with many channels devoted to news twenty-four hours a day and seven days a week such as CNN, Fox News Channel, and MSNBC. The internet is also a very fast growing media for people to get their news, especially for teenagers and people in their twenties. Radio also falls under electronic media. Talk radio is also big in today’s nation with many popular radio hosts such as Rush Limbaugh, Howard Stern, and Dr. Laura Schlessinger. But what makes news media so popular? Is it the right here and right now mindset that the people of today have? There are many things that contribute to this. These next couple of paragraphs is going to explore electronic media and public relations of public media. People love to watch TV. I believe I mentioned earlier that fifty percent of the nation gets their news from television. The fact is that most people get their news from the television. The reason this is that there is non-stop bombardment of news and talk shows on at all times. There are even specific news series and channels that specialize in a certain part of the news such as ESPN for sports coverage, Bloomberg TV for stock market coverage, and Entertainment Tonight for the latest celebrity gossip. These specialty television shows have grown together with the growth of cable television. There are so many different news agencies out there now trying to break the big story that public relations representatives for companies are working over time to make sure that their company is not under attack from a nosey reporter trying to rise in the ranks. It is a recurring nightmare for the public relations department of many big corporations. Katie Couric has a great quote on the subject that sums it all up very nicely: â€Å"Some news  coverage has become more salacious, more sensationalistic, less intelligent, more giving people what they want to hear or what you think they want to hear, rather than what you think they need to or should ideally hear.† Because of news shows being on all the time, there is one very important thing that every public relations people should know how to do and that is handle a television interview. If a public relations person does not know what they are doing when being interviewed, they can potentially hurt the company that they are supposed to be representing. There are many different do’s and don’ts that should be remembered when participating in an interview but I am going to skip right down to the most important part. The biggest two things you need to remember when being interviewed is be honest and be prepared. Television publicity is not always a bad thing. Since most people get their news from television, companies usually will want to take advantage of this phenomenon and go to the general public through television. The way companies do this is through the video news release. The people in public relations most often use the video news release for breaking news. Breaking news video releases are sent by satellite directly to a news agency. There is also another type of video news release that is not for breaking news, which is called evergreen video news releases. Evergreen video news releases are often sent to broadcasters on a cassette. This is the case because of the fact that an evergreen video news release is not necessarily as important so time is usually not an issue. Video news releases are very important for the person who works in public relations. There are many important guidelines to video news releases that should be kept in mind while one is being produced. One of the most important things about producing a video news release is localizing it. A VNR will more likely be used if it can be tailored for specific areas. Another thing that should be remembered about VNRs is that a good VNR tells a story. It does need to be a story tailored to the television viewer. This means that the VNR should be short and to the point with sound bites and graphics. It should appear as if the VNR is just like any other piece of  news on the station. A VNR should not be produced if there is nothing to see. If there is no video or no pictures, then it is a waste of time and money. People will not watch it so broadcasting corporations will not even bother to pick it up. There are some downsides and risks to VNRs. I say risks because just like movies at the movie theater, there are going to be some flops. And also just like movies, VNR producers can lose large amounts of money. A public relations person should make sure that a VNR is needed before producing one. The VNR should also be expensive. Do not cheapen the VNR and cut corners because the broadcasting corporations will recognize this and not waste their airtime. Public relations people should also realize that there are other ways to get the news out to the public. Just because something needs to be reported to the public does not mean that a VNR should be used. Some analysis needs to be taken into consideration to make sure that the VNR is actually the right way to distribute the information. There are some controversies on whether VNRs are an accurate and undeceiving form of news yet overall the VNR is an effective way to get an important message to millions of people. Another form of electronic media that is important for all people that practice public relations is the public service announcements. A public service announcement is basically just a long commercial that is played for no cost. The organizations that use these most often are the ones of the non-profit sort or of corporations that are doing non-profit activities to better their public image. Although public service announcements are on television, they are not seen by many except for the night owls. Most, but not all, of the public service announcements are run between midnight and 6:00AM. This is due to the fact that companies need commercials that bring in revenue and since public service announcements do not do that, they often do not get the prime time spots. Most public service announcements are like commercials that try to get the viewer to take a specific course of action. They are not nearly as significant as the video news release from a public relations standpoint. The radio is the last electronic media that will be talked about. Talk radio has become huge in the United States. Twenty-two percent of Americans listen to talk radio according to Scarborough Research. The growth of talk radio can be pinpointed to two reasons. The first is that many more people now work at home. This is because of the rapid growth of technology. People no longer need to go to the office because they can finish all their work at home. The second reason that talk radio has grown is the fact that people drive all the time. Since it is very dangerous to watch television while driving, most people listen to the radio while getting from point A to point B. There are now talk shows on just about any subject you could possibly be interested in from sports to hypnotism to conspiracy theories. People like to listen to talk radio because it is â€Å"real†. Talk show hosts say what they want to say and are paid to have an opinion. Talk shows are also interactive. It gives the people that listen to the show a voice. You can call in and give your opinion on the matter as well. AM talk radio is dominated by conservative viewpoints such as Rush Limbaugh, a pioneer in talk radio. Talk radio can also be very controversial so media directors need to be very selective, careful, and prepared if planning to be on a talk radio program. Because television and radio have become such a big part of everyday life in the United States, public relations people need to be aware of it and use it to the fullest potential. News on electronic media is a here and now type of media. News needs to be short and pointed to make sure that the viewer does not lose interest. Electronic media is the future so public relations people should be exploring the opportunities now.

Thursday, August 29, 2019

Troop withdrawal from Iraq Research Paper Example | Topics and Well Written Essays - 1000 words

Troop withdrawal from Iraq - Research Paper Example Theories must be substantiated. Claims must be empirically verified. Outcomes must be predicted according to the available evidence. The influence of this latter tendency on modern society has long since left the lofty realm of academia and entered into the popular imagination. Everything is knowable, most especially in matters of a political nature. In this same popular imagination, politicians and leaders are expected to make informed and rational decisions prior to taking action. If those actions lead to disastrous results (of any kind: social, political, economical etc.) they are often investigated as to the poor decisions which brought them about. Hardly ever would a politician attribute his/her failure to â€Å"chance† or â€Å"randomness.† This would appear weak and indecisive. This general area of discussion finds a most appropriate expression in the case of America’s invasion and ongoing occupation of Iraq. As students we are as interested, frustrated, a nd connected to the war in Iraq as anyone else. Since Barack Obama was elected president, the question of an American withdrawal from Iraq has become a pressing and even urgent one for many of those voters who put him into office. The ultimate decision will neither be easy nor simple. A time table is a tricky thing to set for troop withdrawal from Iraq, because of unforeseen and external forces. In his renowned scholarly article entitled â€Å"The Unanticipated Consequences of Purposive Social Action†, the sociologist Robert Merton seeks to demonstrate that a given social or political decision and ensuing action by an elected leader can often end in not only a failure to yield the desired outcome but can also result in an outcome which is antithetical the original goal(s). Merton contextualizes this claim as one which has been expressed by various thinkers in a wide array of disciplines throughout history.

Wednesday, August 28, 2019

Organization's financial statements Essay Example | Topics and Well Written Essays - 750 words

Organization's financial statements - Essay Example In this way, the success of financial analysis process is depended on the use of accurate information, as incorporated in financial statements of each organization. Due to its role in the development of effective organizational decisions, the financial analysis has been extensively explored in the literature. Emphasis has been given to the different missions that financial analysis can achieve, as a decision making tool. It seems that the need for eliminating risks in regard to investment decisions has been the key reason for the expansion of financial analysis process (Lee et al. 2009, p.2). Indeed, it has been proved that financial analysis is an excellent tool for checking whether the existent capital of a firm is adequate for responding to the needs of a particular investment, either in the short or the long term (Lee et al. 2009, p.2). From a similar point of view Norman has argued that financial analysis is quite important for minimizing risks related to the potential participa tion of a firm in a stock exchange market (Norman 2011). Maitah et al. (2012) refer to the use of financial statement analysis in banks as a tool for identifying effective ‘investment and lending decisions’ (Maitah 2012, p.107). ... ? Financial statements most important in financial analysis (Zager & Zager 2006, p.36) Through the financial statement of each organization figures showing the performance of the organization to specific sectors can be retrieved. For example, reference could be made to Liabilities and Shareholders’ equity, as elements of a firm’s balance sheet, one of the most important financial statements of modern firms (Belkaoui 1998, p.2). The financial analysis process can help managers to check the relationship between their firms’ different financial statements; in this way, the actual financial performance of the firm can be identified. The tool used for achieving this target is the financial ration analysis. The above analysis is developed using financial ratios, i.e. figures showing ‘the expression of the relation between two financial statement accounts’ (Drake & Fabozzi 2012, p.102). The analysis of these ratios helps to understand the performance of a f irm in regard to the sectors reflected in these ratios. The most common financial ratios are presented in Figure 2 below. Figure 2 – Most common financial ratios (Zager & Zager 2006, p.38) At this point, the following fact should be highlighted: Financial ratios reflect different aspects of organizational performance. Other ratios refer to the security of the business, as of its financial strength, while others show the financial efficiency of the organization (Zuger & Zuger 2006). This fact is made clear through the graph in Figure 3. Figure 3 – Financial rations as part of the financial analysis process (Zager & Zager 2006, p.39) According to the issues discussed above, financial analysis is necessary for securing the success of organizational decisions. The close relationship between financial analysis and

Tuesday, August 27, 2019

Financial Reporting Disclosures in the Australian Corporate Sector Essay

Financial Reporting Disclosures in the Australian Corporate Sector - Essay Example More, the standards require that the identifiable intangible assets must be disclosed by means of subdividing the assets into classes with similar identifiable intangible assets being grouped together with regards to their usage and operations. Cash generating units impairment testing should be through the process of comparing the carrying amounts of identifiable intangible assets, goodwill working capital, and PPE of the cash-generating units. It is also important to note that valuation approaches during disclosure needs to be financial ratios and discounted cash flow. The company also needs to ensure that sensitivity analysis is done in case there are changes in key assumptions used during financial reporting. The importance of carrying out a sensitivity analysis to changes in key assumptions is due to the need to evaluate variations and their effects on financial reporting. Sensitivity analysis will also enable corrective actions to ensure compliance of financial reporting require ments. According to analysis of the company’s reporting practice, forecast must be corrected to be based on present value of future expected future cash flows. Forecasts on future cash flows must also be based on an established cyclic cash flow pattern. Table of Contents Introduction Identifiable Intangible Assets Impairment Testing on Cash Generating Units Calculation of Discount Rates and Growth Rates Sensitivity analysis to Key Assumption changes Financial Reporting Practice of CCA LTD Recommendations Financial Reporting Disclosures in the Australian Corporate Sector Introduction Corporate companies are subject to Corporations Act, which is being promoted by ASIC reviewers to ensure compliance with financial reporting requirements. The ASIC further provides non-compliance allowance for specific requirements to corporations. Confidence of investors and integrity levels in the Australian Corporate sector is largely boosted by the ASIC activities of monitoring corporationâ₠¬â„¢s compliance to financial reporting requirements. Users of financial reporting and auditing information are able to make informed decisions about the reliability and relevance of financial reporting disclosures in the Australian Corporate Sector. There is need for Coca Cola Amatil LTD to ensure that their financial reporting standards adhere to the professional and legal requirements of the corporations act. The objective of these financial reporting disclosures report is to ensure that Coca Cola Amatil LTD adheres to corporate Act’s requirements of financial reporting disclosures in the Australian Corporate Sector. Identifiable Intangible Assets The corporate act specifies reporting standards that must be adhered to when disclosing information regarding identifiable intangible assets such as names of brands, relationship with customers and written off intangible assets of Coca Cola Amatil LTD. The company should disclose identifiable intangible assets that would have bee n recognized during business formation or combinations and research and development assets. These intangible assets do not include assets that are recognized through contract basis or any other means that is legal. During financial reporti

Monday, August 26, 2019

Foundation of the League of Nations Research Paper

Foundation of the League of Nations - Research Paper Example The Covenant of the League of Nations consisted of short preambles that were developed for the major three objectives and it was drafted in Article 26 of the League of Nations. There were several articles drafted by the League of Nations to address the members regarding the conditions of members, admission and withdrawal, power, nature of the Council and Assembly (Institute for International Law and Justice, â€Å"The Covenant of the League of Nations†).   In case of the disputes between the members and the obligations, rules and regulations were amended and new articles were introduced. To practically apply the peace policy and maintain security, articles were drafted (Tufts University, â€Å"The Covenant of the League Of Nations†).   Success of the LeagueThere were no set standards in Europe before the World War I relating to the management of employed individuals. The League of Nations, in order to develop labor conditions globally with International Labor Organi zation, fixed maximum working hours per day and week. The member countries were specified to mention the minimum wages, benefits of employees and pensions. This step was known to be of great success for the League of Nations. The League was also successful in providing the first passport for the stateless refugees. This was known as the Nansen passport that was the identification of these people (Bowen, â€Å"Understanding International Relations†). The dispute between Finland and Sweden in 1920 regarding the Aaland Island was solved by the League. There were many islands between Sweden and Finland mid-way that generated conflicts between them. Germany and Poland had conflicts between them regarding the industrial area of Upper Silesia. In 1921, the League was successful in solving the conflict and

Sunday, August 25, 2019

Football Essay Example | Topics and Well Written Essays - 1250 words

Football - Essay Example What is driving sports in the world is more than just fun. In the new era, sport has become a combination of management, responsibility, skill-development, rivalry, strategy, fitness and many more aspects one can think of as this domain can not be limited or confined to a few principles. Football Stadiums are all over the world and people do not hesitate to fill in the stadiums regardless of what so ever the match is. This sport brings in much revenue as well. A single ticket in Manchester for a match between the famous rivals Manchester United and Arsenal can cost well over 500 which is way above many developing economies' GDP per capita. At this stage, the concept of a "Team" is most important. The word team does not refer only to a group of people combined to accomplish a task rather it is an association of individual who socialize and cope with each other's differences to reach the "maximum" achievable. A team consists of members that have different skills so each can be a specialist in any one desired area. The team members also have complementary skills to coordinate well and imply synergy so as lessen or hide an individual's weakness in that of the team's strength. The highlight of the modern sport is "Football". It is the most popular sport of the world. It has players from all across the world. Lets see what football is and how did it trace its origin. Our predecessors have been accustomed to playing a game/sport that involved kicking the ball around a specified area and targeting a desired point. The issue was that one team had to put the ball through and the other had to stop. In the early times the sport was played by almost every Race, Tribe, Stronghold but the rules varied a lot. So we can say that football has been a global sport for quite a time. The earlier versions were the "Chinese game of cuju" and the "Harpastum" as played by the Romans. The need to develop standardized rules was felt in the mid 19th century as the sport was gaining much popularity and was spreading. The first to come up were the Cambridge Rules as many British schools ought to play the game thus uniformity was required. Research Methodology The research will be based on surveys and short interviews with general people from different areas. Selecting this methodology will bypass any bias present in the research. The problem would be to classify the data into groups and arrange it accordingly. The surveys would be internet based and some site visits. We can easily find Football fans across the world and so it would be feasible if shopping Malls are targeted for this purpose. The survey would consist of small questionnaire placed at the exit of the Mall and the public would be required to just give in a few minutes answering the questions if they are interested. Further at other convenient places, small interviews highlighting the sporting events and globalization of Football will be undertaken by an experienced interviewer such that the results could be analyzed and summarized easily. Selection Feasibility Why have I chosen this topic is because Football requires

Saturday, August 24, 2019

The Persuasive Research Paper Essay Example | Topics and Well Written Essays - 1000 words - 2

The Persuasive Research Paper - Essay Example It is for this reason that they are as prosperous today as they ever were. The opposite happens in countries like the Philippines. It is apparent that most Filipinos do not effectively recognize the full worth of their indigenous traditions, institutions and capabilities. They revere other countries but neglect their own. It is ironic how the Philippines is classified as a Third World nation noted for corruption, poor governance, poverty, and a low total industrial capacity considering it has nearly everything any nation needs for great development: a strategic location, abundant natural resources and a rich supply of human capital. The only thing separating it from becoming a world power is the shortfall of self-confidence in its people. Because nationalism triggers a country’s movement toward a more prosperous future, the Filipino people’s lack thereof continues to be the root of the slow development of the Philippines. The Filipinos are the product of their colonial history. Almost four hundred years of colonization significantly disturbed the people’s mental framework, giving birth to a deep-seated colonial mentality that hindered them from showing enough concern for the national interest, which consequently slowed down the country’s rate of development. In its place, it encouraged Filipinos to believe that other nations were better than them. This, in time, ingrained itself into what is now seemingly a natural trait. At the outset, the Philippines did not come together before the Spanish settlement. It was not even a country before the Spaniards arrived and colonized the islands. In fact, the Philippines was a mere archipelago of small autonomous divisions known as barangays. As said by Guarià ±a in his historical essay, it was the Spanish settlement that unified the Philippines into a country. At the same time however, it formed Filipino societies that took little pride in their own nation and instead only deified their colonizers. As a

Friday, August 23, 2019

ENGLISH Essay Example | Topics and Well Written Essays - 500 words - 4

ENGLISH - Essay Example She and Brandon went out a few months ago, but he suddenly dumped her. Arianna went white-cold every time Anna asked why they broke up. Then, the most joyous day happened. Brandon asked Anna out. It was a gloomy day with black heavy clouds threatening a storm. He was with his friends when Anna was walking home. He said: â€Å"Hey Anna, wow you look so grown up and beautiful. I want to invite you over at my house. Just some movies and stuff.† His friends sniggered. Anna didn’t care. She was in heaven and tried to look like she thought about it first before saying a nervous â€Å"Okay.† His friends left them. Inside the house, they watched a porn movie. It made Anna uncomfortable. The video looked amateur. Boys were breathing deeply at the background and it was dark. Brandon groped her breasts and whispered: â€Å"Let’s do it.† Anna said no, but she felt dizzy and weak. She looked groggily at her glass of soda. Brandon forced himself on her, while his friends videotaped the act. Anna couldn’t breathe. When she glanced at the movie they were watching, the video looked clearer and she saw Adrianna’s face down, her tears rolling, while Brandon grunted like a pig behind

Thursday, August 22, 2019

Why quit smoking Essay Example | Topics and Well Written Essays - 750 words

Why quit smoking - Essay Example There are many instances where the smokers give up the habit and then succumb to the temptation. This is because they have made only half-hearted measures to quit smoking and unless one is completely determined to quit, the desire would manifest again and again. Some of the measures like reducing the number of cigarettes one smokes or increasing the interval between successive cigarettes are just temporary solutions and do not lead to any long term de-addiction. There has to be a strong willed desire to quit and the resolve has to be stiff. Though these may seem like harsh words, unfortunately they are the ones that can help in smoking cessation. - There are many who believe that â€Å"tapering† off nicotine usage can lead to quitting smoking. However, studies have indicated that the majority of smokers who quit have done so by abruptly quitting instead of tapering over a period of time. This method calls for will power and resolve and certain modifications to the dietary habits can make a difference. If one can reduce the intake of caffeine, sugar and alcohol, they go a long way in making one move away from nicotine. These are stimulants that aid in a cycle of substance addiction and cessation of any one of these can lead to cessation of the other. The high risk groups are those who take one or more than one of these stimulants in large quantities. - Quitting smoking improves the physical and mental fitness of individuals. So, having an exercise regimen goes a long way in aiding the urge to quit smoking. As they say, a jog around the park can be more addictive than a pack of cigarettes. - The effect of the peer group is one of the most important factors in people deciding to smoke and conversely deciding to quit as well. So, make sure that you get the encouragement of co-workers and friends who do not smoke and try to minimize the

Network Security Essay Example for Free

Network Security Essay You are interested in starting your own Music Store, QualitySounds, in a suburban area of your town. You need to design and build a network and computing solution for your stores. You have done some initial planning and you will start with two stores (but you plan to add two more stores across town within one year). Your store will sell new and used music and allow customers to get â€Å"online† in your stores and download music. You also will offer classes on how to setup music downloads and configure MP3 devices. You took computer networking courses in college and you feel you can tackle this solution yourself. Upon initial planning, you have identified the following requirements for your network: * Connects three office computers and one computer used for Point-of-Sale (POS) services at each of your stores. You also want six (6) computers in the lobby/store where patrons can download music and you can run â€Å"training classes† for people to learn about using MP3 players and get other basic information. The two offices have to be connected into one cohesive network, sharing POS services and other critical company information. You also need to provide a â€Å"hand out† casual area for people to stop in and discuss music and connect wirelessly to the Internet (you might even offer free coffee to entice people to come in to your store). * Provides adequate security for all of the company communications and documents (especially sensitive sales documents). All POS services must be protected. All general network access should be segmented from the company POS services. * Fast and have additional capacity as the company grows * Provides for centralized printing * Supports the eventual addition of other stores to the network * Provides customers with a general information Website and a secure Website where clients can buy services, and products * Provides for limited downtime (24 hour downtime maximum) * Provides for centralized management and control of the computers in the two stores, so that you can maintain the network from off-site * Provides for long-term cost effectiveness * Provides a suite of software tools for the employees to effectively communicate and a POS solution for the stores The company does not have any equipment. Your plan should include a complete network and computer system that meets these requirements and future expansion plans. The two store locations will (eventually) be within a five-mile radius of each other. The locations are within a suburban area that has current technological infrastructures and related technology offerings. The stores will need a sales system and print services for invoices. Complete your proposal including costs for computing equipment, network infrastructure, network servers, printers, and related hardware, software, and accessories. Include as much detail as possible as well as justification as to your selections. Diagram and explain your physical network and computer design as well as the logical network design (server installation, domain layout, etc.). As you are a small business, cost is a major factor and should be minimized.

Wednesday, August 21, 2019

Political And Economic Stability In Singapore

Political And Economic Stability In Singapore MICE industry is increasing rapidly and create tremendous amount of profits worldwide in tourism sector. MICE stand for meeting, incentives, conferences and exhibition which driving ahead as a key growth driver. The MICE industry plays a very important role and economic contributor in Singapores tourism industry. There are many factors that makes Singapore become a major MICE destination in the world. Singapore is working hard to stay on top of the competitive business event arena and now Singapore is ranked as the top convention city in Asia for ninth times. Singapore has the first class conventions venue such as Singapore Expo. Besides, Singapores pro business environment, multi-ethnic landscape, strategic geographic location and multi lingual populace has attract many business travellers prefer to do their business tourism in Singapore. With its strategic location, government support and all those strengthen factors; it makes Singapore boost them to hit the highest achievement in this sector. The influencing factors are divided into few different categories. 1.2 Problem Statement This research is about how Singapore develops themselves to become a major MICE destination among the world. At the moment, they are doing a very great job as a MICE destination in Singapore. In fact, there are several factors that influence Singapore as a MICE destination. 1.3 Research Question What is MICE industry all about? What are the major factors that influence Singapore as a major MICE destination in the world? What makes Singapore become a major MICE destination in the world? The forecast be for this sector in Singapore and why? What makes Singapore continuously attracts high profile and highly rated international business events? What have Singapores government done in order to boost up their MICE industry among the world? 1.4 Research Objective This research is going to find out the factors that influence Singapore as a major MICE destination in the world. By carry out this research, the MICE industry in Singapore has growth rapidly and future lifestyle as well. Besides, there is also the understanding of how importance MICE industry that could affect Singapores tourism sector and to find out the reason why business travelers loyalty toward Singapore as their favorite MICE destination. Lastly, this research also show the evaluate business travelers benefit and interest by organizing an event in Singapore. 1.5 Conceptual Framework Define MICE industry in Singapore Strategic Location Critical Mass Communication Infrastructure Stability political and economic in Singapore The major factors that influence Singapore as a major MICE Destination in the world Excellent transportation system and telecommunication connectivity. Excellent meeting and conference venue. Pro Business environment and governments support The forecast be for this sector in Singapore Figure 1.1 According to this figure 1.1, it illustrates the major factor that influences Singapore as a major MICE destination in the world. The purpose of showing this figure is to demonstrate the topic of this report. The theory framework will show the reason why Singapore can become a ideal MICE destination to the business travellers. Firstly, this research shows aspect that could influence Singapore as a major MICE destination. Besides this, the report also shows how Singapore develops their MICE industry in tourism sector. Lastly, will be the evaluation of forecast for this sector in Singapore. 1.6 Scope and Limitation The scope for this research is to focus on Singapore MICE industry. Besides that, is to observe how Singapores MICE industry growth rapidly within these few years, how they develop their MICE industry in order to increase the amount of tourist and to predict Singapores MICE industry in the future. The time constraint will be the limitation as this research paper due to the study period of time which is from January 2010 to June 2010. It s about half year time, due to the limited time the researcher may face the difficulties when finding the resources and getting the information from journals, online journals, newspaper, websites, books and etc. There is only limited and restricted literature for Singapore MICE industry that is related in the journal databases such as EBSCO Host, Ebrary, and Google Scholar, and some of the sources that provided were not up to date. But this is a challenge for me to do more on this research. Significance of the Study This research aims to gain an understanding on how Singapores MICE industry growth rapidly in tourism sector. To carry out this research, Singapore is working hard and put themselves out on top of the challenging business events field. This research is very important and very useful. Through this research, the targeted readers which are interested in organize a conference event in Singapore can refer to and to find out the reason why Singapore can be a major MICE destination in the world by maintains their quality and their MICE facilities. Other than that, this research could recommend targeted readers to choose Singapore as their ideal MICE destination. Chapter 2 Review of the Related Literature 2.1 MICE Industry in Singapore MICE industry is increasing rapidly and create a tremendous amount of profits worldwide in tourism sector. MICE are acronym of meeting, incentives, conferences and exhibition which driving ahead as a key growth driver. Europe and North America has been stated as one of the front MICE destination but Asia also one of the country that involves a lot in this industry. Singapore is not an exception. The MICE industry plays a very important role and economic contributor in Singapores tourism industry. A new era of tourism development and attractions will be gearing up for major revitalization by Singapores tourism sector; it will also re-define Singapores tourism landscape. Singapore has the first class conventions and exhibition facilities such as SINGAPORE EXPO and SUNTEC Singapore international convention exhibition centre. In addition, Singapore has outstanding communication infrastructure, it provides more convenience to tourist travel from one place to another domestically and internationally. Singapores pro business environment, multi-ethnic landscape, strategic geographic location and multi lingual populace has attract many business travellers prefer to do their business tourism in Singapore and accompaniment by MICE facilities, infrastructure, expertise and proficient in event management. Singapore put themselves out on top of the challenging business events field. Singapore MICE industry has grown rapidly and now Singapore is ranked the world top three cities for meetings by the Unions of International Associations (UIA). Apparently Singapore has been stated and positioned as the Top Convention City all around Asia for ninth time and the Third Top Convention City around the world for the second consecutive year by ICCA Ranking. Singapore has leapfrogged two score to reach on top of the ranking, defeating Paris and Vienna and providing its goal to be the top of the universe an improvement. 2.2 The factors that could influence Singapore as a major MICE destination in the world. There are many factors that can manipulate Singapore to become a major MICE destination in the world and it also could affect their tourism sector by increase MICE events in their own country. The factors also can be consider as their strength mean while it is a positive factor that can enhance their MICE sector to becoming the Best City for MICE events among the world in the future. 2.2.1 Critical Mass The most important factor is it has critical mass; it has been awarded by the Union of International Association (UIA) and Asias top convention city for several years. By developing a critical mass of MICE event is this industry, this will helps to create an eco-system of business event that harmonize one anothers existence. Business event not only generate enliven of MICE industry in the mean time its also build up Singapores value intention as a MICE destination. For the past few years, Singapore has increase the amount of international meetings. These shows from the creativity and quality of the Singapore MICE industry and construct Singapore constantly catch the attention of high-profile international business event. 2.2.2 Strategic Location Secondly, Singapore has a strategic geographic location which is central location in Asia and also a connection between east and west. It also acts as key district hubs for Asia. This strategic location makes Singapore exert a pull on global businesses and it smoothly links around the world. There were few big events of different industries was held in Singapore such as Asia Aerospace, Food Hotel Asia, Communic Asia and Broadcast Asia and etc. The feedback was great. Singapore is a safe hospitable country; this is also one of the reasons that event organizers choose Singapore. Beside this, Singapore Changi Airport is also one of the busiest airlines in the world, which connects to over 180 cities in 50 countries and is categorize as a premier International Maritime Centre. Its wide ranging air and sea linkages allow ones business to allowed 2.8 billion people within a seven hours flight radius. Singapore Tourism Board claims that Singapore position attest to its appeal as a premium business travel and meetings, incentive travel, convention and exhibition destination 2.2.3 Stability political and economic in Singapore Singapore has a good reputation of efficient, honest and politically stable government compare to other countries. Singapores stability of political gives the trust of safe for business travellers to decide to organise events in Singapore. Singapore is a knowledge-based economy and attracts worldwide investments. This may attract foreign investors flock its shores because of their open trade procedure, social stability, world class infrastructure and international communication links. The stability of Singapores economic also will raise the amount of business travellers invest in promoting their product in Singapore. The IMD World Competitiveness Yearbook 2008 stated that Singapore as the worlds second most competitive economy. The stability political and economic growth is sustain by the government of Singapore, it helps to attract more business travellers to held their event in Singapore with no burden compare to their competitors such as Malaysia and Hong Kong. 2.2.4 Communication Infrastructure Singapore is well known by their efficiency and good communication infrastructure have allow it to attract a whole train of international events including the Asia-Pacific Economic Cooperation (APEC) meetings in 2009 and the forth coming event will be the first-ever summer Youth Olympic Games which falls on 14th August 2010 to 26th August 2010. Singapore also attracts business travellers to contribute to its achievements as a main destination for both business and entertainments. Singapore has rated the top in terms of basic infrastructure and technology infrastructure in the World Competitiveness Yearbook. Its efficiency through latest technology and modern infrastructure makes Singapore MICE industry speedily grow in tourism industry. 2.2.5 Pro Business environment and Government Support Singapore is recognized as a PRO business environment and its recommended as the most beneficial place in the world for businessman to start their business there. In facts, Singapore has been noted as No 1 in terms of Ease of Doing businesses for the past four years by the World Bank. Singapore is one of the lowest corporate and income tax rates among the most of the countries. The government has improves the firm environment to help business manage more efficiently. Singapore has effectively reached a good amount of association meetings by its well-built business basics and plans to assemble a active ecosystem of business events. Singapore Tourism Board (STB) said All vital signs are pointing towards the return of business confidence in the Singapore business event sector, fuelled by dynamic developments taking place within the tourism landscape. Leverage in our sterling track record and a sound business fundamental, Singapore has secured a robust pipeline of business events, including key international association meeting in coming years. The general pro-business environment gives Singapore a competitive boundary as a major MICE destination in the world. There is another reason that makes Singapore become a PRO business environment and MICE destination because of the strongly government support through Singapore Tourism Board (STB), government support was the key to make an event successful. Singapores government give fully support in this sector and contributes Singapore as a vibrant business environment. Singapore devoted a lot in promoting the MICE business and also their tourist attractions because conventions and event have the ability to make more profits and jobs in short term and it can increase the interrelated investment and the amount of visitation on longer term. The Singapore Exhibition and Convention Bureau (SECB), a group of the STB has develop the Business Events in Singapore (BE in Singapore) its help business events organizers release a higher amount of events. Besides, Singapore Tourism Board (STB) also launched another campaign Make It Singapore and it helps to offer marketing support and motivation to potential MICE business. Furthermore, Singapore is has the professionalism in the MICE industry that can makes Singapore to be a global exchange core where people can gather and share their ideas and knowledge. 2.2.6 Excellent meeting and conference venue and offers venue Singapore is a global core for business and leisure and it is also a best option for convention and events. The excellences of hotel ballrooms and with the first class convention centres, Singapore has continuously recreates with new event location and attraction such as Marina Bay Sands Singapore. Marina Bay attractions will create a unique MICE venue that we cannot found elsewhere in Asia with international standard MICE facilities and services. MICE facilities in Marina Bay Sands, Singapore Expo, Suntec International Convention and Exhibition Centre are amalgamate to boost Singapores attractiveness as a business and leisure destination. Suntec Singapore International Convention and Exhibition Centre and Singapore Expo are defined as a favourite choice for all find of business event due to their huge exhibition spacious. A good convention centre, exhibition halls and meeting venue plays a very important role when we organize an event. 2.2.7 Excellent Transportation System and Telecommunications Connectivity Singapore posses of efficiency and excellent public transportation system, which includes cabs, buses and the modern Mass Rapid Transport (MRT) rail system same goes to their air transportation. Tourists can get around in Singapore with no burden due to their excellent transport system. An outstanding network of railway system and buses connect travellers to reach any point of the city and the public transportation prices are reasonable to everyone. Singapore provides convenience for foreign business travellers to reach any destination, conference venues and attractions with their public transport system on time due to their punctuality of railway systems. The newly opened MRT network has made ease of access to conference venue such as Suntec Singapore and Singapore Expo, it made convenient for those business travellers. Beside this, Singapores bus network is tremendously frequent and extensive and it does not only bring convenient to Singapores citizen and also tourists. Singapore is well recognized for their public transportation and telecommunications connectivity. According to a survey carried out by Singapores Land Transport Authority in year 2006, 8 out of 10 Singaporeans were satisfied with their public transportation system such as buses and also railway system, Singapore has 21 Tbps of installed international communication infrastructure capacity, adequate for every business require in telecommunications connectivity. They are one of the more aggressive telecommunication hubs around Asia Pacific. They also provide excellent telecommunication links with broadband network all around business hotels, so those business travellers can surf the internet anytime when inside the hotel room. 2.3 Forecast Singapore MICE industry in the future. From my point of view, I strongly believe that Singapore will finalize to the top spot and becoming the Best City for MICE venue in the future. Singapore will also be leading ahead of other countries. Singapores tourism background is going through a dynamic transformation. On year 2010, there will be more cityscape that gives off more vibrant and enthusiasm on the atmosphere. Singapore are still innovating themselves by introducing newly, modern venue and outstanding facilities to give their foreign business travellers and demonstrators a pleasure knowledge and ambience. They will also keep up their status as Asias premier MICE destination through recommending new transportation system and entertainments. The Asia-Pacific is likely to attract over 100 million business travellers and MICE visitors by 2015 with the growth prospective in the region. Therefore there will be no surprise that Singapore to become a bigger slice of this MICE market. With its stability political and global economy shows signs of reflect, the business event sector is in good chance of taking advantage of on business opportunities. In the upcoming years, Singapore will keep a strong pipeline of business occasion, including the key international association meetings. Ms Melissa Ow, Assistant Chief Executive, Business Travel and MICE Group, Singapore Tourism Board (STB) said: As we move into 2010, and climate of economy recovery the STB will continue to work closely with our industry partners to meet business event organisers evolving needs, explore new business leads and strengthen our international marketing and channel development efforts. Marina Bay sands will be one of the improvement into an amalgamate MICE venue which offers 200,000 square meter of convention and exhibition space which create and grow strategic business occasion. These developments will redefine Singapores downtown and central business region. There are estimate more than 150,000 meeting attendees are to stopover Singapore for those events that already booked at the Marina Bay Sands. Besides, Resort World Sentosa has accommodated 35,000 attendees at a single event. Marina Bay Sands said that it has secured more than 30 events development to be held there from this year to 2012. On the year of 2010, the worlds first -ever summer Youth Olympic Games will be hosted by Singapore. With approximately arrival of 15,000 overseas participants and visitors bring about 180,000 or more visitor to Singapore. Beside this, Singapore is also hosting a series of upcoming events and meetings in these few years, such as International Cruise Terminal 2010, Gardens by the Bay 2010, Sports Hub 2010, National Art Gallery 2013 and many more. Singapore will continue to expand their abilities and upgrading their infrastructure to provide business event travellers in order to guarantee their position as one of the top Asian. Singapore Tourism Board (STB) has planned to upgrade the facilities of Singapore Expo to make sure Singapore Expo is well-organized to sustain the development of MICE industry. The upgraded facilities will ensure Singapore Expo retains their excellent venue for business events. There are many growing competitors out there from other country such as Malaysia, Hong Kong, Thailand, Macau and etc. But Singapore is making every chance to offer good facilities and services to their business event travellers. Besides, STB are working continuously closely with the events industry. The main purpose is to increase the amount of the business event at Singapore and to make sure that the MICE sector continues to move ahead as a key driver of tourism development in Singapore. Lastly, I personally think that Singapore has performed well in this industry and lead Singapore to be on top of the MICE industry, because during the staging events in Singapore, the event organiser can be assured of their quality service, accompanied by its tremendous transportation and professional workforce. Although Singapore has obtain a lot of awards but they dont feel self-esteem, they keep on their good work and maintaining their facilities to achieve and make them the best MICE destination in the world. Furthermore, Singapores MICE industry is on the roadway and I strongly believe that if Singapore put in more efforts on this industry, it can leapfrog to reach the top and becoming the Best City for MICE events among the world in the future. Chapter Three Research Methodology 3.1 Research Method For the methodology, this research will be using questionnaire. Among quantitative method and qualitative method, I use both of the method for my research. It is also known as a mix of approaches. The first method is quantitative method which is a technique to gather quantitative data such as information dealing with numbers and anything that is measurable. While for the qualitative method is to understand the meaning of the numbers produced by quantitative method. We have to observe case analysis with given research imply to qualitative methods and quantitative methods to request respondents to rank their perception about these particular topic. 3.2 Research Design There are two types of research method which is qualitative method and quantitative method. Qualitative method is more on observation and quantitative method is subjective. Qualitative method need to collect date based on quality and is difficult to generalize because everyones perception is different; meanwhile it may affect the quality of the result. For the quantitative method, it is more objective compared to qualitative method because the data must be fact and logic. And it will be in numbers and also in statistics such as graphs or tables. It is essential to use both methods to understand the core of this research. 3.3 Data Collection Apparently the data in this report is collected from the secondary data which is online database. Secondary data can be easily found at journal, articles, websites, textbooks, books and etc. The researcher gets the journal from the college library website and it is mainly taken from the Google Scholar and EBSCO Host.

Tuesday, August 20, 2019

Galactosemia Disorder: Causes, Forms and Treatments

Galactosemia Disorder: Causes, Forms and Treatments Abstract: Carbohydrates are vital for energy in all living organism and also in the biosynthesis of essential glycoconjugates. One of these carbohydrates is a monosaccharide called galactose which is broken-down in humans by the Leloir pathway of the galactose metabolism.[1] Within this pathway, there are three main enzymes that is responsible for modifying galactose in order to convert it into glycolysis for the production of energy – galactokinase (GALK1), galactose-1-phosohate uridyl transferase (GALT), and galactose-6-phosphate epimerase (GALE). A deficiency in any of these enzymes results in a disorder in the human called galactosemia. The second enzyme of this pathway, GALT which produces uridine diphosphogalactose (UPD-gal) from galactose-1-phosphate (gal-1P), a deficiency in this is the most severe of the three galactosemia disorders. GALK1 is rare and the symptoms are much milder than that of GALT with the rarest of the disorder being GALE. Galactosemia is established shortly a fter an infant starts feeding and even though a strict galactose-free diet is introduced promptly eliminating any acute symptoms, the long-term complications unfortunately has already taken place. While early detection can lead to relatively normal life, this inherited disorder is unable to break down simple sugar called galactose and with excessive buildup causes liver, brain, and eye damages. Introduction: All living organism make use of carbohydrates or sugars for the formation of cellular energy along with the synthesis of essential cellular glycoconjugates. In humans, we not only consume carbohydrates but we’re also able to synthesize altered carbohydrate monomers by means of reversible metabolic pathways. Galactose is typically in many of our dairy products that we consume as a carbohydrate monomer which is part of the disaccharide lactose. The human body is able to break down galactose using the Leloir pathway of galactose metabolism. This pathway consists of three enzymes, each structuring a different metabolic intermediate functioning together to accomplish one objective and that is to modify galactose into glucose in order to release it into glycolysis for the production of energy. The three enzymes are, Galactokinase (GALK1), galactose-1-phosohate uridyl transferase (GALT), and galactose-4-phosphate epimerase (GALE). An absence or mutations in any of these enzymes resul ts in a disorder in the human called galactosemia. The second enzyme of this pathway, GALT which produces uridine diphosphogalactose (UPD-gal) from galactose-1-phosphate (gal-1P), a deficiency in this enzyme is the most severe of the three galactosemia disorders. GALK1 is rare and the symptoms are much milder than that of GALT causing cataracts of the eye with the rarest of the disorder being GALE with acute symptoms as in GALT. UDP-gal in the Leloir’s pathway plays crucial role in synthesizing several essential glycoconjugates along with ultimately being used for energy production. GALT deficiency in humans’ results in a disorder called galactosemia, a potentially fatal disorder if left untreated immediately after birth. Galactose Metabolism (Leloir Pathway): Figure 1. Galactose Metabolism (Leloir Pathway) in the Liver. The galactose metabolic pathway, also known as Leloir pathway named after Luis Federico Leloir who revealed the principal mechanisms of galactose metabolism and defining the cause of galactosemia.[2] This is the only mechanism of galactose metabolism in humans which contains three enzymes, galactokinase (GALK1), galactose-1-phosphate uridyl transferase (GALT), and galactose-4-phosphate epimerase (GALE) which are responsible for their respective role in the Leloir pathway.[3] Upon entrance of the cell, galactose is first phosphorylated by GALK to yield galactose-1-phosphate, which is one of the two substrates of GALT. From here, GALT modifies it further to one uridine diphosphogalactose and one glucose-1-phosphate from one uridine diphosphoglucose and one galactose-1-phosphate. The expected product of GALT, UDP-gal, is the substance of GALE. As GALE epimerizes UDP-gal to produce UDP-glu, which is modified furthermore to enter glycolysis or be used as UDP-glu to synthesize necessary glycoconjugates in the cell.[4] [5] Further modification of UDP-glu consist of the loss of uridine monophosphate in order to produce glucose-1-phosphate. The mutase enzyme then yields glucose-6-phosphate, a glycolytic intermediate that moves into glycolysis to harvest energy in the form of ATP.[6] Since galactose is an essential component of many glycoconjugates, some UDP-gal is used for the synthesis of these sugar moieties which highlights the significance of GALT in the meta bolism and cellular consumption of galactose.[7] Galactosemia: Galactosemia is an autosomal recessive inborn error in the metabolism which affects how the body breakdown the sugar galactose with a rate of about 1 in 62,000 individuals.[8] As a result, those individuals with galactosemia has difficulty digesting this simple sugar that are often found in many foods which is primarily part of a larger sugar called lactose. Lactose produces one molecule each of the simple sugar glucose and galactose which is nearly found in all dairy products and baby formulas.[9] The disorder is typically diagnosed soon after birth, as infants are either breast-fed or formula-fed. However these newborn starts to express characteristic complications that tend to develop after the consumption of milk over a short period of time like nausea, vomiting, jaundice, and lethargy.[10] The accumulation of galactose is toxic to the body if not digested by the appropriate enzyme quickly causes serious health complications to the newborn. Treatments currently involves managemen t of galactose-free diet, although some drug tests in the disorder process have been proposed. Laboratory tests are available to confirm of the disease by measuring the enzyme activity of galactose-1-phosphate uridyl transferase or GALT which is the second step in the pathway of galactose metabolism.[11] There are 3 forms of this disorder: galactose-1-phosphate uridyl transferase (GALT), galactose kinase (GALK1), and galactose-4-phosphate epimerase (GALE) with each form having a relative differences in severity. Those individuals who expresses any of these disorders will have elevated levels of galactose in their blood along with high levels of galactose in the urine. For this reason, hospitals now carry out galactose tolerance tests which are now considered essential for the identification of the disease. Once confirmation of this disorder has been done, the newborn is treated using a dietary galactose restriction by replacing breast or milk base-formula with soy base-formula. Although most of the prominent features of this disease will improve such as nausea, diarrhea, cataracts, or enlarged liver and spleen will gradually regress once placed on the dietary restriction there is one chief symptom which does not show much improvement which is mental retardation due to the damage of the central nervous system.[12] It’s for this reason, that early diagnosis and prompt therapy are crucial. Cause of Disorder: Galactosemia means â€Å"galactose in the blood†, since these individuals are not able to break down galactose to produce energy, this sugar therefore builds up in their blood resulting in high levels of galactose-1-phosphate in the tissues. The pathway for galactose is more complex than most other simple sugars with three enzymes that are essential to convert a molecule of galactose into glucose-6-phosphate. Therefore, any type of genetic mutations in any part of the galactose pathway will cause severe life altering changes effecting organs and intellectual capacity if not treated right away. We can see from Fig. 1 that there are multiple steps in the breakdown of galactose into glucose-1-phosphate and be able to enter into glycolysis where it is broken down into glucose our main energy source. The GALK1 is the first enzyme in the galactose pathway and from this figure we can clearly see how by a mutation in GALK1 could cause so much chaos in the breakdown of galactose. The ability for our bodies to breakdown galactose into glucose plays a crucial for life. As a result, individuals with galactosemia, the GALT enzyme is either missing or not working properly and therefore unable to digest galactose into glucose causing large buildups in the blood. Overtime, this buildup if remain untreated will develop into fatality and although certain damages are able to regress a few of the many will not be irreversible. Forms of Disorder: There are several forms of galactosemia which are caused by mutations of a specific gene affecting different enzymes that are involved in the process of breaking down galactose. The classic galactosemia or galactose-1-phosphate uridyl transferase (GALT) is also known as galactosemia type I, is the most common and severe form of this disorder. Classical galactosemia affects 1 out of 60,000 newborns. In the classic galactosemia, infants are born without the GALT enzyme and are either fed breast-milk or milk-base formulas. In newborns nearly 90% of their carbohydrates comes from lactose, human breast milk comprises of nearly 6% to 8% lactose and most infant formulas comprises of 7% lactose.[13] Therefore all these milk-based products are immediately substituted with lactose free formulas such as soy-based formulas to lessen any further damage to the newborn. Fortunately, most cases of classic galactosemia are detected early enough by newborn screenings and a galactose-free diet is quickly put in place. Within galactosemia type I, there is a rare type of galactosemia called â€Å"Duarte variant†, it is often but not always detected during newborn screening since this is a milder form requiring less treatment or in most cases, no treatment but an erythrocyte GALT enzyme activity test may be performed to confirm this variant form of the disease. Galactokinase deficiency (GALK1) is also known as galactosemia type II which is rare genetic causing cataract damage due to a lack of galactokinase.[14] Galactosemia type II affects fewer than 1 out of 100,000 newborns. GALK1, is responsible for one step in the galactose metabolic pathway that converts galactose to galactose-1-phosphate which is then converted to glucose. A mutation in this gene results in galactose and an associated sugar called galactitol to buildup in the cells that constructs the lens of the eye.[15] With high level of these accumulations in the blood will damage the lens which will cause cataract and lead to blurred vision – a characteristic in galactosemia type II. Galactose-4-phosphate epimerase deficiency (GALE) is also known as galactosemia type III and the rarest of the three forms of galactosemia. Those who have this may have mild to severe symptoms which may include cataracts, delayed growth and development, along with liver disease, and liver problems. There has not been many reported with the GALE mutations as this is the fewest of the galactosemia disorders. GALE, is an enzyme that instructs the production of an enzyme called UPD-galactose-4-epimerase and responsible for converting UDP-galactose to UDP-glucose. Since GALE is the rarest of the disorder, those affected with galactosemia type III may or may not have any of the complications characteristically related to galactosemia and often do not require treatment. In general, those who have this disorder whose had high level of these enzymes in the blood will still lead to complications such as damaged tissues or organs, cataract, to intellectual disabilities and damages to the liver, kidneys and brain.[16] Newborn Screening: With the high rate of associated with untreated individuals, newborn screening for galactosemia and other inherited genetic disorders are available in all of the 50 states and provinces of the United States. To screen for galactosemia, infant blood and urine samples are screened for the presence of GALT and any galactose metabolites.[17] The samples are first tested for the concentration of galactose and GALT activity, and if galactose levels are high and/or GALT activity is low, then the samples are then assayed for galactose-1-phosphate and further tested of the more common DNA mutations associated with galactosemia.[18] . GALT enzyme presence of less than 32  µmol/L (normal 150-500  µmol/L) is usually indicative of GALT-deficient galactosemia.[19] Newborn screening is essential in early detection and treatment of galactosemia patients efficiently. It is vital to their physical and mental health to avoid as much damage to the individual as possible. Studies has shown that approximately 80% of children given newborn screening for galactosemia were diagnosed within 2 weeks of age, compared to approximately 35% of whom were not screened. From those whom were screened 20% were free of GALT deficiency symptoms at the time of diagnosis.[20] Although nutritional therapy is frequently used which gradually improves the symptoms in patients with galactosemia disorders by introducing these individuals to a galactose-free diet.[21] In most cases, as long as the disease has not advanced too much, most of all acute symptoms gradually regress and often times completely disappear with dietary restriction alone. Many newborns will show rapid weight gain along with no more nauseating or vomiting. The organs like the liver and spleen that would be enlarged due to excess galactose in the body also returns to normal size along with cataracts, if present, will start to regress and most of the time will disappear completely.[22] Unfortunately, there is one significant symptom that shows no signs of improvement – mental retardation or intellectual disability like speech defects and other neurological or physiological abnormalities.[23] Since newborn screening is not performed until at least 24 hours after an infant has begun feedi ng, galactosemia infants will consume galactose before being diagnosis. A more efficient and timely screening methods are necessary to decrease the cases of infants who are already exhibiting disease symptoms at the time of diagnosis. Diet: The most common and most effective form of treatment so far for galactosemia is dietary restriction of galactose consumption. By having galactosemia patient avoid lactose or ingesting food containing galactose they are able to minimize any further damage to their body. For infants, it’s particularly imperative as lactose is present in all milk-base products and studies has now shown that there are some free-galactose in some fruits and vegetables. A study by Gross and Acosta in 1991 indicated monomeric galactose contents in approximately 45 different fruits and vegetables. For example, artichoke, mushrooms, olives, and peanuts all contained less than 0.1 mg of free galactose per 100 mg of plant tissue. In persimmon and tomato contained approximately 34.5 mg of free galactose per 100 g of plant tissue. Fruits and vegetables like dates, papaya, bell pepper, and watermelon were found to have upwards of 10 mg of free galactose per 100 g of plant tissues.[24] Conclusion: Although uncommon due to the effective newborn screening, undiagnosed galactosemia can lead to liver cirrhosis, mental retardation, and even death. [25] Girls with galactosemia have been found in later years to have higher rates of ovarian failure even with dietary intake. It’s important to understand that with acute symptoms at birth can managed with diet but the long-term affect involving impaired sexual and mental function are still prevalent among galactosemia individuals. References: Antshel, K. M., Epstein, I. O., Waisbren, S. E. (2004). Cognitive strengths and weaknesses in children and adolescents homozygous for the galactosemia Q188R mutation: a descriptive study. Neuropsychology, 18(4), 658-664. Hardin, J., Bertoni, G., Kleinsmith, L.J., (2012) Becker’s World of the Cell, 8th Ed, International Edition. Pearson Education, Inc. Glenview. pp. 242 Isselbacher, K.J. (1957), Clinical and Biochemical Observations in Galactosemia. The American Journal of Clinical Nutrition. Vol. 5, No. 5, pp. 527-532. Grossiord, B. P., Luesink, E. J., Vaughan, E. E., Arnaud, A., de Vos, W. M. (2003). Characterization, Expression, and Mutation of the Lactococcus lactis galPMKTE Genes, Involved in Galactose Utilization via the Leloir Pathway. Journal of Bacteriology. Vol. 185, No. 3, pp. 870-878. Kalckar, H. M., Kurahashi, K., Jordan, E. (1959). â€Å"Hereditary Defects in Galactose Metabolism in Escherichia Coli Mutants, I. Determination of Enzyme Activities†. Proceedings of the National Academy of Sciences of the United States of America, Vol. 45, No. 12, pp. 1776-1786. Asada, M., Okano, Y., Imamura, T., Suyama, I., Hase, Y., Isshiki, G., (1999). Molecular characterization of galactokinase deficiency in Japanese patients. Journal of Human Genetics. Vol. 44: 377-382. Lai, K., Langley, S. D., Khwaja, F. W., Schmitt, E. W., Elsas, L. J. (2003). GALT Deficiency Causes UDP-Hexose Deficit in Human Galactosemic Cells. Glycobiology. Vol. 13, No. 4, pp. 285-294. Berry, G.T., Classic Galactosemia and Clinical Variant Galactosemia. 2000 Feb 4 [Updated 2014 Apr 3]. GeneReviews ® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2014.http://www.ncbi.nlm.nih.gov/books/NBK1518/ Ai, Y., Zheng, Z., O’Brien-Jenkins, A., Bernard, D.J., Wynshaw-Boris, T., Ning, C., Reynolds, R., Segal, S., Huang, K., and Dwight Stambolian. (2000), A Mouse Model of Galactose-Induced Cataracts. Human Molecular Genetics. Vol. 9, No. 12, pp. 1821-1827. Fridovich-Keil, J.,Bean, L., He, M., andRichard Schroer., Epimerase Deficiency Galactosemia. 2011 Jan 25 [Updated 2013 Oct 24]. GeneReviews ® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2014.http://www.ncbi.nlm.nih.gov/books/NBK51671/ Freer, D. E., Ficicioglu, C., Finegold, D. (2010). Newborn Screening for Galactosemia: A Review of 5 Years of Data and Audit of a Revised Reporting Approach. Clinical Chemistry, Vol. 56, No. 3, pp. 437-444. Waggoner, D. D., Buist, N. R., Donnell, G. N. (1990). Long-term Prognosis in Galactosaemia: Results of a Survey of 350 Cases. Journal of Inherited Metabolism Disorder., Vol. 13, No. 6, pp.802-818. Gross, K. C., Acosta, P. B. (1991). Fruits and Vegetables are a Source of Galactose: Implications in Planning the Diets of Patients with Galactosemia. Journal of Inherited Metabolism Disorder, Vol. 14, No.2 253-258. ~ 1 ~ [1] Kurt J. Isselbacher, â€Å"Clinical and Biochemical Observations in Galactosemia.† The American Journal of Clinical Nutrition 5 (September-October 1957): 527-532. [2] Benoit P. Groissard et al., â€Å"Characterization, Expression, and Mutation of the Lactococcus lactis galPMKTE Genes, Involved in Galactose Utilization via the Lenoir Pathway.† Journal of Bacteriology 185 (February 2003): 870-878. [3] Herman M. Kalckar et al., â€Å"Hereditary Defects in Galactose Metabolism in Escherichia Coli Mutants, I. Determination of Enzyme Activities.† Proceedings of the National Academy of Sciences of the U.S.A. 45 (December 1959): 1776-1786. [4] Groissard, 870-878. [5] Kalckar, 1776-1786. [6] Groissard, 870-878 [7] K. Lai et al., â€Å"GALT Deficiency Causes UDP-hexose Deficit in Human Galactosemic Cells.† Glycobiology 13 (January 2003): 285-294. [8] Boris B.T. Wang et al., â€Å"Molecular and Biochemical Basis of Galactosemia.† Molecular Genetics and Metabolism 63 (1998): 263-269. [9] Jeff Hardin et al., Becker’s World of the Cell (Glenview: Pearson Education Inc., 2012), 242002E [10] Isselbacher, 527. [11] Wang, 263. [12] Isselbacher, 528. [13] Gerard T. Berry, MD., â€Å"Classic Galactosemia and Clinical Variant Galactosemia.† GeneReviews ® [Internet] – NCBI Bookshelf (1993-2014). [14] Minoru Asada et al., â€Å"Molecular Characterization of Galactokinase Deficiency in Japanese Patients.† Journal of Human Genetics 44 (1999): 377-382. [15] Yunjun Ai et al., â€Å"A Mouse Model of Galactose-Induced Cataracts.† Human Molecular Genetics 9 (2000): 1821-1827. [16] Judith Fridovich-Keil, PhD et al., â€Å"Epimerase Deficiency Galactosemia.† GeneReviews ® NCBI Bookshelf (2011-2013). [17] Dennis E. Freer, Can Ficicioglu, and David Finegold., â€Å"Newborn Screening for Galactosemia: A Review of 5 Years of Data and Audit of A Revised Reporting Approach.† Clinical Chemistry 56 (March 2010): 437-444. [18] Freer et al., 437-444. [19] Freer et al., 437-444. [20] D.D. Waggoner, N.R M. Buist, and G.N. Donnell., â€Å"Long-term Prognosis in Galactosemia: Results of A Survey of 350 Cases† Journal of Inherited Metabolic Diseaase 13 (November 1990): 802-818. [21] Isselbacher, 528. [22] Isselbacher, 528. [23] Wang, 263. [24] K.C. Gross and P.B. Acosta., â€Å"Fruits and Vegetables Are A Source of Galactose: Implications in Planning the Diets of Patients with Galactosemia.† Journal of Inherited Metabolic Disease 14 (1991): 253-258. [25] Kevin M. Antshel et al., â€Å"Cognitive Strengths and Weaknesses in Children and Adolescents Homozygous for the Galactosemia Q188R Mutation: A Descriptive Study.† Neuropsychology 18 (October 2004): 658-664.